Author

Diego Japon-Ruiz

Université Libre de BruxellesORCID 0009-0007-3842-9522Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aurora Vigato· 1 shared Benjamin BeckiD· 1 shared Fabiana MoresiiD· 1 shared Marta Ávalos-MorenoiD· 1 shared Xavier BisteauiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

Aurora Vigato

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJul 17, 2026

Cisplatin-Induced Plasticity Drives Cross-Resistance to CDK4/6 Inhibitors and Reveals Targetable Vulnerabilities Through HDAC Inhibition in Esophageal Squamous Cell Carcinoma.

Marta Ávalos-Moreno, Aurora Vigato, Fabiana Moresi…·Xavier Bisteau

This study shows cisplatin resistance in ESCC leads to an immune-evasive, drug-tolerant state that confers cross-resistance to CDK4/6 inhibitors, which can be reversed by HDAC inhibitors.

DOI 10.64898/2026.07.17.738886

humanbulk RNA-seq

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