Megan L. Schumacher

This study shows that both C4HSL and PqsE are essential for RhlR-dependent gene expression in Pseudomonas aeruginosa clinical isolates, revealing a conserved regulatory module for virulence.

This study identifies PhoPQ as a regulator of quorum sensing in small colony variants of Pseudomonas aeruginosa, showing its role in virulence factor production and subpopulation adaptation.

This study identifies key residues in RhlR that determine ligand specificity and shows how ligand-driven gene regulation affects phenazine gene expression in Pseudomonas aeruginosa.

This study compares HCMV replication efficiency in epithelial cells using viruses produced from fibroblasts or epithelial cells, finding higher titer and syncytia formation with epithelial-derived virus.

This study shows that HCMV can infect and replicate in terminally differentiated human cortical neurons, causing structural and functional changes including altered calcium signaling and neurotransmission.

The paper investigates how the source of HCMV affects neuronal pathogenesis in cerebral organoids and shows that neutralizing antibodies and neurotropic factors can mitigate gene expression dysregulation.