Cell BiologyLife Science AlliancePeer-reviewed
Aberrant NSUN1 Activity Connects m5C RNA Modification to TDP-43 Neurotoxicity in ALS/FTD
Melissa Parra-Torres, Kumara Dissanayake, James A. Gray…·Leeanne McGurk
This study identifies NSUN1-mediated m5C RNA methylation as a driver of TDP-43 cytoplasmic accumulation and neurotoxicity in ALS/FTD.
DOI 10.26508/lsa.202503297