Ziyao Shen

This paper shows that AAV2-hAIBP preserves retinal ganglion cells and visual function in glaucoma without lowering intraocular pressure by targeting neuroinflammation through the AIBP-TLR4 axis.

The paper identifies AKAP1 as a critical regulator of mitochondrial and synaptic homeostasis in glaucoma, showing its role in neuroprotection and axon regeneration through gene therapy in mouse models.

This study shows that restoring AIBP expression in glaucomatous retinas protects retinal ganglion cells and reduces neuroinflammation in mouse models.

This study shows that activating soluble adenylyl cyclase (sAC) protects retinal ganglion cells from oxidative stress by preserving mitochondrial function and structure.