Sinwoo Hwang

This paper shows that AAV2-hAIBP preserves retinal ganglion cells and visual function in glaucoma without lowering intraocular pressure by targeting neuroinflammation through the AIBP-TLR4 axis.

This study shows that restoring AIBP expression in glaucomatous retinas protects retinal ganglion cells and reduces neuroinflammation in mouse models.

This study shows that reduced Shmt2 expression causes mtDNA leakage into the cytosol, triggering different downstream effects like apoptosis or activation of the cGAS/STING pathway in different cell types.