Therapeutic AIBP expression contributes to synaptic preservation and vision restoration against glaucomatous neuroinflammation
Tonking Bastola, Sinwoo Hwang, Ziyao Shen, Soo-Ho Choi, Seunghwan Choi, Esther Jang, Muna Poudel, Keun-Young Kim, Yury I. Miller, Robert Neal Weinreb, Won‐Kyu Ju
This paper shows that AAV2-hAIBP preserves retinal ganglion cells and visual function in glaucoma without lowering intraocular pressure by targeting neuroinflammation through the AIBP-TLR4 axis.
bioRxiv · Oct 12, 2026 · PreprintNeuroscience