Cell BiologyNature AgingPeer-reviewed
Targeting CyclinD1-CDK6 to Mitigate Senescence-Driven Inflammation and Age-Associated Functional Decline
Adarsh Rajesh, Aaron P. Havas, Rouven Arnold…·Peter D. Adams
This study shows that targeting CCND1-CDK6 reduces DNA damage, inflammation, and age-related decline in mice by suppressing SASP and ISG expression.
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