Author

Vinesh Jarajapu

Moffitt Cancer CenterORCID 0009-0007-8877-3292Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Florian A. KarrethiD· 2 shared Neel JasaniiD· 2 shared Xiaonan XuiD· 2 shared Benjamin PosorskeiD· 1 shared J. William HarbouriD· 1 shared James Jarad DollariD· 1 shared Jeffim N. KuznetsoffiD· 1 shared Jiqiang YaoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Florian A. KarrethORCID

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2 papers

Recent·Most cited

Cancer BiologyOncogenePeer-reviewedNov 24, 2025

FRA1 drives melanoma metastasis through an actionable transcriptional network

Xiaonan Xu, Vinesh Jarajapu, Manon Chadourne…·Florian A. Karreth

This study identifies FRA1 as a driver of melanoma metastasis and shows that targeting its downstream genes AXL, CDK6, and FSCN1 suppresses metastasis and improves survival.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJun 4, 2025

A multi-step immune-competent genetic mouse model reveals phenotypic plasticity in uveal melanoma

Xiaonan Xu, Xiaoxian Liu, James Jarad Dollar…·Florian A. Karreth

This paper develops a genetically engineered mouse model of uveal melanoma that recapitulates human disease progression and immune microenvironment features, revealing phenotypic plasticity and cooperative genetic drivers.

2 citations

mousescRNA-seq

𝕏 PostBluesky