NeurosciencebioRxivPreprint
Midbrain organoids with an SNCA gene triplication display dopamine-dependent alterations in network activity
Ghislaine Deyab, Rhalena A. Thomas, Xue Er Ding…·Edward A. Fon
This study shows that midbrain organoids with SNCA gene triplication exhibit PD-like neural activity changes, which can be reversed by dopamine agonists.
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