Tinaïg Le Borgne

This study investigates how the gut-brain vagal axis influences mesolimbic dopamine dynamics and reward behaviors, challenging the traditional brain-centric view of reward processing.

This study shows that dopaminergic activity in the ventral tegmental area shapes social roles and labor division in mouse triads through competitive and cooperative strategies.

This study investigates the role of dopamine D2 autoreceptors in regulating VTA dopamine neuron responses to aversive stimuli and finds they act as a regulatory brake with sex-biased effects on threat processing.

The paper shows nicotine inhibits amygdala-projecting dopamine neurons via a VTA-NAc feedback loop, leading to anxiety.

This study shows that dopamine signals in the nucleus accumbens reflect dynamic representation learning during adaptive decision-making in mice.

This study shows that adolescent nicotine exposure disrupts dopamine circuit development, leading to adult vulnerability to nicotine, which can be reversed by restoring dopamine pathway balance.

This study identifies distinct dopamine circuits in the ventral tegmental area that mediate nicotine's reinforcing and anxiogenic effects through opposing responses in neurons projecting to the nucleus accumbens and amygdala.