Maria Otero‐Jimenez

This study shows that temporal interference stimulation enhances neural progenitor cell maturation in vitro and promotes hippocampal neurogenesis in a mouse Alzheimer's model.

The paper introduces an in situ seeding immunodetection assay to visualize alpha-synuclein and tau seeding activities with high spatial resolution in intact tissues, revealing neuron-driven alpha-synuclein seeding in Parkinson's disease before clinical symptoms.

The paper uses single-cell Mendelian randomisation to identify cell-type specific genetic effects on brain disease and behaviour, revealing 118 genes with causal associations to 16 brain phenotypes.