Author

Alyma Somani

UCL Queen Square Institute of Neurology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Maria ThomiD· 2 shared Alexander HaglundiD· 1 shared Alexi NottiD· 1 shared Amy M. SmithiD· 1 shared André AltmanniD· 1 shared Andrea BernasconiiD· 1 shared Andrea CherubiniiD· 1 shared Andreja AvberšekiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Maria ThomORCID

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2 papers

Recent·Most cited

Single-cell Mendelian randomisation identifies cell-type specific genetic effects on human brain disease and behaviour

Alexander Haglund, Verena Zuber, Maya Abouzeid, Yifei Yang, Jeong Hun Ko, Liv Wiemann, Maria Otero‐Jimenez, Louwai Muhammed, Rahel Feleke, Alexi Nott, James Dominic Mills, Liisi Laaniste, Djordje O. Gveric, Daniel Clode, Ann C. Babtie, , Michael R. Johnson

The paper uses single-cell Mendelian randomisation to identify cell-type specific genetic effects on brain disease and behaviour, revealing 118 genes with causal associations to 16 brain phenotypes.

Nature Genetics · Jan 10, 2025Peer-reviewedNeuroscience

A systems-level analysis highlights microglial activation as a modifying factor in common forms of human epilepsy

André Altmann, Mina Ryten, Martina Di Nunzio, Teresa Ravizza, Daniele Tolomeo, Regina Hertfelder Reynolds, Alyma Somani, Marco Bacigaluppi, Valentina Iori, Edoardo Micotti, Rossella Di Sapia, Milica Cerovic, Eleonora Palma, Gabriele Ruffolo, Juan Antonio Botía, , Annamaria Vezzani

The paper identifies microglial activation as a factor contributing to cortical thinning in epilepsy by integrating neuroimaging and gene expression data.

Neuropathology and Applied Neurobiology · Aug 13, 2021Peer-reviewedNeuroscience