Phuong M. Le

This study identifies declining Wnt signaling as a driver of age-related alveolar stem cell loss and shows that restoring Wnt signaling in aged mice improves lung repair but not full regeneration.

This study shows that α-catenin phosphorylation, regulated by actomyosin contractility, is essential for epithelial barrier function through its interaction with Afadin.

The paper shows that α-catenin phosphorylation during mitosis prevents apical rounding and epithelial barrier leak by strengthening cell-cell interactions.