Author

Alexandra J. McCraw

King's College LondonORCID 0009-0008-2412-4389Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Alice Kosmider· 1 shared Alicia M. ChenowethiD· 1 shared Anthony CheungiD· 1 shared Daniela IancuiD· 1 shared Dongjun GuoiD· 1 shared Franca FraternaliiD· 1 shared Jitesh ChauhaniD· 1 shared Joseph Chi-Fung NgiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alice Kosmider

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1 paper

Recent·Most cited

ImmunologymAbsPeer-reviewedJul 13, 2025

Tuning antibody stability and function by rational designs of framework mutations

Joseph Chi-Fung Ng, Alicia M. Chenoweth, Maria Laura De Sciscio…·Franca Fraternali

This study designs framework mutations in antibodies to improve stability and function using a computational-experimental approach, showing that FW modifications can affect immunological functions beyond binding affinity.

3 citations

protein structuredeep learning

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