Author

Shaili Mathur

Stanford UniversityORCID 0009-0008-3438-4897Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Dmitri A. PetroviD· 2 shared Olivia M. GhoshiD· 2 shared Abhishek DuttaiD· 1 shared Alexandra N. KhristichiD· 1 shared Clare I. AbreuiD· 1 shared Jean C. C. VilaiD· 1 shared Jonas CremeriD· 1 shared Joseph SchachereriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 26 mutual co-author links

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2 shared papersEvolutionary Biology

Dmitri A. PetrovORCID

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2 papers

Recent·Most cited

Evolutionary BiologybioRxivPreprintOct 2, 2026

Order invariance of fitness makes evolution predictable despite strong history-dependent effects

Shaili Mathur, Clare I. Abreu, Olivia M. Ghosh…·Dmitri A. Petrov

The paper tests how environmental order affects the fitness of yeast mutants and finds that overall fitness is largely invariant to order due to compensatory history-dependent effects.

DOI 10.64898/2026.09.29.755513

yeastexperimental assay

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Evolutionary BiologybioRxivPreprintOct 9, 2025

Adaptive evolution can overwrite initial natural fitness variation only in highest-fitness yeast isolates

Alexandra N. Khristich, Olivia M. Ghosh, Jean C. C. Vila…·Dmitri A. Petrov

This study shows that high initial fitness is necessary but not sufficient for long-term success in yeast, as adaptive mutations can override small fitness differences.

1 citation

yeastDNA methylation

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