Abhishek Dutta

The paper develops a barcoded yeast collection to map genotype-phenotype relationships across genetic diversity, revealing genetic variants linked to chemical responses.

This study shows that high initial fitness is necessary but not sufficient for long-term success in yeast, as adaptive mutations can override small fitness differences.

The paper analyzes meiotic recombination landscapes across five yeast species, finding species-specific differences in recombination rates, crossover interference, and hotspot conservation.

The paper analyzes meiotic recombination in Lachancea waltii, identifying differences in crossover distribution, LOH events, and recombination hotspots compared to related species.

This study examines LOH event frequency and spectrum across different ploidy levels in yeast isolates, finding higher LOH rates and specific tract biases in polyploids.

The paper identifies mlh3 alleles with distinct separation of function phenotypes in meiosis and DNA mismatch repair, revealing the role of protein-protein interactions in regulating Mlh1-Mlh3 activity.