Anna Campalans

The paper shows oxidative DNA damage directly affects gene transcription through repair-dependent mechanisms using RNA-Seq, ChIP-seq, and chemogenetic approaches.

This study shows that NTHL1 loss increases mtDNA copy number and mitochondrial function, enhancing cellular resilience to oxidative stress through stress response pathways.

The paper demonstrates that OGG1 uses coordinated amino acids to efficiently detect 8-oxoG lesions in DNA.

This study shows that the G-quadruplex ligand RHPS4 reduces radioresistance by inhibiting mitochondrial adaptations caused by ionising irradiation.

The paper shows that metallic nanoparticles are taken up more by mesenchymal breast cancer cells via the HA-CD44 axis, suggesting potential for targeted therapies.

This study shows that fetal exposure to BPA analogs causes DNA oxidation, leading to meiotic defects and oocyte aneuploidy in mice.

MasterPATH analyzes functional genomics screening data using network analysis to identify active molecular pathways associated with specific phenotypes.