Author

Y Otani

University of LiverpoolORCID 0009-0008-6049-1135Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Benjamin Thomas GoultiD· 2 shared Juha SaarikangasiD· 2 shared Neil J. BalliD· 2 shared Vignesh Srinivasan· 2 shared Emily GoodalliD· 1 shared Hans‐Jürgen KreienkampiD· 1 shared Igor BarsukoviD· 1 shared Julia Töller· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Benjamin Thomas GoultORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 10, 2026

An internal PDZ-binding motif in Densin-180 promotes activity-dependent SHANK scaffold remodelling

Y Otani, Vignesh Srinivasan, Julia Töller…·Benjamin Thomas Goult

This study identifies an internal PDZ-binding motif in Densin-180 that promotes SHANK scaffold remodelling through activity-dependent interactions.

DOI 10.64898/2026.07.07.736929

statistical model

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 27, 2025

Cyclin-dependent kinase-like 5 (CDKL5) binds to talin and is anchored at the postsynaptic density via direct interaction with PDZ domains

Y Otani, Emily Goodall, Vignesh Srinivasan…·Benjamin Thomas Goult

This paper identifies how CDKL5 is anchored at the postsynaptic density via interactions with PDZ domains and talin, and shows that its spatial positioning is regulated by talin's mechanical properties.

DOI 10.1101/2025.08.27.672337

humanproteomics

𝕏 PostBluesky