Author

Emma Mohlmann

Boston Children's HospitalORCID 0009-0008-6245-3677Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Amy E. O’ConnelliD· 1 shared Amy ShepherdiD· 1 shared Bianca Frintu· 1 shared Claudio Henrique T. RibeiroiD· 1 shared Daniel ZeveiD· 1 shared David T. BreaultiD· 1 shared Diana L. CarloneiD· 1 shared Elisa Saint‐Denis· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

Amy E. O’ConnellORCID

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2 papers

Recent·Most cited

Cancer BiologyJournal of Biological ChemistryPeer-reviewedAug 10, 2026

Insulin receptor substrate 2 (IRS2) confers resistance to PI3K pathway inhibition in PIK3CA mutant breast cancer

Michael W. Lero, Jennifer S. Morgan, Michael-Anthony Card…·Leslie M. J. Shaw

This study identifies IRS2 as a mediator of resistance to PI3K pathway inhibitors in PIK3CA mutant breast cancer by sustaining PI3K signaling through FOXO3-mediated regulation.

DOI 10.1016/j.jbc.2026.113426

humanbulk RNA-seq

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Cell BiologybioRxivPreprintJun 5, 2026

EGFR INHIBITION PROMOTES ENTEROENDOCRINE CELL DIFFERENTIATION CONTRIBUTING TO TREATMENT-ASSOCIATED DIARRHEA

Guilherme Piovezani Ramos, Daniel Zeve, Amy Shepherd…·David T. Breault

This study identifies EGFR inhibitors as inducers of enteroendocrine cell differentiation, linking their use to treatment-associated diarrhea through STAT1 signaling activation.

DOI 10.64898/2026.06.02.729650

humanmouse

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