Author

Amin Fahim

Goethe University FrankfurtORCID 0009-0008-7529-9592Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Robert TampéiD· 3 shared Lukas Sušac· 2 shared Simon TrowitzschiD· 2 shared Christoph NockeriD· 1 shared Filippo ManciaiD· 1 shared Ines Katharina MülleriD· 1 shared Lisa Saggau· 1 shared Matija Pečak· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

Robert TampéORCID

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3 papers

Recent·Most cited

ImmunologyThe EMBO JournalPeer-reviewedAug 17, 2026

Reconstitution of glycan-driven MHC I recycling reveals calreticulin as mediator between TAPBPR and tapasin

Tim Julius Heinke, Amin Fahim, Niko Popovic…·Robert Tampé

The paper reveals calreticulin mediates glycan-dependent transfer of MHC I from TAPBPR to tapasin, essential for MHC I recycling and quality control.

DOI 10.1038/s44318-026-00873-2

humanproteomics

𝕏 PostBluesky

BiochemistrybioRxivPreprintNov 27, 2025

Single-molecule dynamics reveal ATP binding alone powers substrate translocation by an ABC transporter

Christoph Nocker, Matija Pečak, Tobias Nocker…·Robert Tampé

The paper uses single-molecule FRET to show ATP binding alone drives peptide translocation by TmrAB without Mg2+.

3 citations

fluorescence / live-cell microscopyexperimental assay

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ImmunologybioRxivPreprintJun 25, 2025

US6 hijacks the peptide-loading complex by trapping transporter-chaperone dynamics

Milena Stolz, Lukas Sušac, Amin Fahim…·Robert Tampé

This paper reveals how the HCMV protein US6 inhibits the peptide-loading complex by altering TAP dynamics, providing insights into viral immune evasion mechanisms.

1 citation

humanstructural biology

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