Author

Sylvain Chollet

University of LausanneORCID 0009-0008-7769-844XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:genetic perturbation / CRISPR· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alexis A. JourdainiD· 3 shared Emeline RecazensiD· 2 shared Mads Møller FogediD· 2 shared Miriam LisciiD· 2 shared Abigail StrefeleriD· 1 shared Anna LysakowskiiD· 1 shared Boris ZinshteyniD· 1 shared Christian MünchiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

Alexis A. JourdainORCID

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3 papers

Recent·Most cited

Cell BiologyCell ReportsPeer-reviewedJul 25, 2025

An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Meniere disease

Marcell Harhai, Mads Møller Foged, Christine Zarges…·Alexis A. Jourdain

10 citations

humangenetic perturbation / CRISPR

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BiochemistrybioRxivPreprintMar 11, 2025

Uridine-sensitized screening identifies genes and metabolic regulators of nucleotide synthesis

Abigail Strefeler, Zakery N. Baker, Sylvain Chollet…·Alexis A. Jourdain

The paper identifies genes and metabolic regulators of nucleotide synthesis using uridine salvage and CRISPR-Cas9 screening, revealing NUDT5's role in maintaining nucleotide balance and its impact on chemotherapy resistance.

6 citations

humanmetabolomics

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Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedNov 6, 2024

Cytosolic N6AMT1-dependent translation supports mitochondrial RNA processing

Mads Møller Foged, Emeline Recazens, Sylvain Chollet…·Alexis A. Jourdain

The paper identifies N6AMT1's role in cytosolic translation of mitochondrial RNAse P subunits, showing its necessity for mitochondrial RNA processing and function.

11 citations

humanbulk RNA-seq

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