Systems BiologyCell Host & MicrobePeer-reviewed
Coronavirus protein interaction mapping in bat and human cells identifies molecular and genetic switches for immune evasion and replication
Jyoti Batra, Magdalena Rutkowska, Yuan Zhou…·Nevan J. Krogan
Author
Shivali Malpotra
Gladstone InstitutesORCID 0009-0008-8274-6709Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2025-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 papers
Recent·Most cited
- BiochemistryeLifePeer-reviewed
Coupled equilibria of dimerization and lipid binding modulate SARS Cov 2 Orf9b interactions and interferon response
CJ San Felipe, Jyoti Batra, Monita Muralidharan…·James S. Fraser
This study develops a biophysical model to show how lipid binding and mutations affect Orf9b's conformational equilibrium and its interaction with Tom70, influencing interferon suppression.
- MicrobiologyNature MicrobiologyPeer-reviewed
Transcriptional plasticity of virulence genes provides malaria parasites with greateradaptive capacity for avoiding host immunity
Francesca Florini, Joseph E. Visone, Evi Hadjimichael…·Kirk W. Deitsch
This study reveals that Plasmodium falciparum parasites can express multiple var genes or suppress var gene expression, enabling them to evade host immunity and persist in chronic infections.
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