Author

Anna Vinken

University Medical Center UtrechtORCID 0009-0009-1012-9143Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Beatriz G. CarvalhoiD· 1 shared Daniëlle KootiD· 1 shared Floris FoijeriD· 1 shared Hugo J.G. SnippertiD· 1 shared Irene C. ZaalbergiD· 1 shared Martijn J.M. VromansiD· 1 shared Meritxell Brunet GuaschiD· 1 shared Michael D. NicholsoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Beatriz G. CarvalhoORCID

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1 paper

Recent·Most cited

Chromosome 7 gain establishes a just-right WNT signaling state during colorectal tumorigenesis

Irene C. Zaalberg, Paula C. Gasull, Martijn J.M. Vromans, Meritxell Brunet Guasch, Natalia Marcekova, Anna Vinken, Sjors Middelkamp, René Wardenaar, Daniëlle Koot, Beatriz G. Carvalho, Hugo J.G. Snippert, Michael D. Nicholson, Floris Foijer, Michaël Schubert, Susanne M. A. Lens

This study shows that chromosome 7 gain optimizes WNT signaling in colorectal cancer by counteracting excessive stemness from APC mutations.

bioRxiv · Oct 14, 2026 · PreprintCancer Biology