Author

Nathalie Sakakini

InsermORCID 0009-0009-1250-922XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Iris ManosalvaiD· 2 shared Salvatore SpicugliaiD· 2 shared Agata CieślakiD· 1 shared Andreas ZanzoniiD· 1 shared Antoine PintoniD· 1 shared Aurore TouzartiD· 1 shared Brian J.P. HuntlyiD· 1 shared Carla Cardone· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCancer Biology

Iris ManosalvaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 26, 2026

Epromoter 3D interaction-associated regulation in T-acute Lymphoblastic Leukemia

Joaquin Felipe Roca Paixão, Iris Manosalva, Antoine Pinton…·Salvatore Spicuglia

This study identifies Epromoters involved in 3D promoter-promoter interactions that regulate gene expression and are critical for T-ALL cell survival.

DOI 10.64898/2026.08.25.746923

humanChIP-seq

𝕏 PostBluesky

GenomicsThe EMBO JournalPeer-reviewedJan 3, 2026

Epromoters bind key stress-related transcription factors to regulate clusters of stress response genes

Juliette Malfait, Jing Wan, Himanshu Narayan Singh…·Salvatore Spicuglia

The paper identifies Epromoters as cis-regulatory elements that regulate clusters of stress-response genes by recruiting key transcription factors, showing their role across different stress models.

4 citationstop 5%

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 25, 2024

Mutational synergy with CREBBP loss in lymphomagenesis identified through forward insertional mutagenesis in a new DLBCL mouse model

Nathalie Sakakini, Roy Straver, Dhoyazan Azazi…·Brian J.P. Huntly

DOI 10.1101/2024.03.25.586554

mouseexperimental assay

𝕏 PostBluesky