Author

Gaofeng Fan

ShanghaiTech UniversityORCID 0009-0009-1445-4832Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Chao XuiD· 1 shared Chenglin MiaoiD· 1 shared Chengyuan WangiD· 1 shared Chenxi TianiD· 1 shared Dake LiiD· 1 shared Dongliang XuiD· 1 shared Fang BaiiD· 1 shared Jiali ZhangiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

Chao XuORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 5, 2025

Tumor hypoxia adaptation depends on FLAD1 mediated mitochondrial metabolic reprogramming

Xiangyu Zhao, Tao Wu, Sanan Wu…·Xuesong Liu

The paper identifies FLAD1 as a key gene for hypoxia adaptation in tumors and develops a deep learning model to predict hypoxia-dependent metabolic genes.

DOI 10.1101/2025.03.05.641576

humanbulk RNA-seq

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Cell BiologybioRxivPreprintFeb 27, 2025

A novel vimentin variant from tumor-associated macrophages directs cancer metastasis by engaging IGF-1R

Chenglin Miao, Xuedi Gao, Jingjing Mao…·Yaming Jiu

This study identifies a novel vimentin variant secreted by tumor-associated macrophages that promotes cancer metastasis by activating IGF-1R and increasing integrin expression.

1 citation

humanproteomics

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Molecular BiologyeLifePeer-reviewedApr 26, 2022

FER-mediated tyrosine phosphorylation and PIK3R2/p85β recruitment on IRS4 promotes the PI3K-AKT signaling pathway and tumorigenesis in ovarian cancer

Yanchun Zhang, Xuexue Xiong, Qi Zhu…·Gaofeng Fan

The paper identifies FER-mediated tyrosine phosphorylation of IRS4 and its role in activating the PI3K-AKT pathway, contributing to ovarian cancer tumorigenesis.

27 citations

humanexperimental assay

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