Fang Bai

The paper identifies two inhibitory mechanisms regulating MYRF-1 cleavage in C. elegans, showing their role in controlling developmental timing.

PhysDock predicts protein-ligand complexes using a physics-guided diffusion model, achieving state-of-the-art performance in redocking and cross-docking benchmarks.

The paper identifies FLAD1 as a key gene for hypoxia adaptation in tumors and develops a deep learning model to predict hypoxia-dependent metabolic genes.

PhenoScreen predicts compound-induced phenotypic changes by linking chemical space to cellular morphology using contrastive learning, showing effectiveness in osteosarcoma and rhabdomyosarcoma.

This study identifies CIB2 as a Ca2+ sensor in auditory mechano-electrical transduction and links TMC1 genetic variants to hearing loss through structural and functional analysis.

This paper introduces GeminiMol, a molecular representation model that incorporates conformational space profiles to improve performance on molecular property prediction and zero-shot tasks like virtual screening.

This study reports the structure of Mtb IrtAB in different states, revealing its mechanism for importing iron-loaded siderophores through ATP-driven conformational changes.

Baicalin and baicalein from Scutellaria baicalensis inhibit SARS-CoV-2 3CL protease non-covalently; a 2.2 Å baicalein complex structure shows an unusual shield-like binding mode.