Nadège Sarrazin

This study shows that MS patient-derived lymphocytes in a chimeric mouse model drive smoldering lesion pathology, impair functional recovery, and alter CNS cell populations and myelination.

This paper presents a non-human primate model of optic nerve demyelination that recapitulates key features of MS lesions, showing failed remyelination, axonal degeneration, and visual dysfunction.

This study shows that loss of floor plate Netrin-1 disrupts corticospinal tract midline crossing in mice, causing mirror movements similar to human congenital conditions.