Anne Baron‐Van Evercooren

Development of a Humanized Mouse Model for Studying adult Spinal Cord myelination, remyelination and Drug Efficacy

This paper develops a humanized mouse model to study human oligodendrocyte maturation, remyelination, and drug efficacy in spinal cord injury.

Failed remyelination of the non-human primate optic nerve leads to axon degeneration, retinal damages and visual dysfunction.

This paper presents a non-human primate model of optic nerve demyelination that recapitulates key features of MS lesions, showing failed remyelination, axonal degeneration, and visual dysfunction.

Beneficial contribution of iPSC-progeny to connexin 47 dynamics during demyelination-remyelination

The paper investigates how iPSC-derived neural progeny affect connexin 47 dynamics during demyelination and remyelination, showing their role in panglial network reconstruction.

Multiple sclerosis iPSC-derived oligodendroglia conserve their intrinsic properties to functionally interact with axons and glia in vivo

The paper shows MS-derived oligodendroglia can myelinate axons and form functional connections in a mouse model, suggesting the differentiation block is due to environmental factors, not intrinsic deficits.

Activation of macrophages by lysophosphatidic acid through the lysophosphatidic acid receptor 1 as a novel mechanism in multiple sclerosis pathogenesis.

This study shows that LPA1 receptor dysregulation in macrophages contributes to MS pathogenesis by promoting inflammation, with implications for therapeutic targeting.

Blood vessels guide Schwann cell migration in the adult demyelinated CNS through Eph/ephrin signaling

This study shows that Schwann cells migrate along blood vessels in the demyelinated CNS via Eph/ephrin signaling, avoiding myelin and interacting with ECM components.