Author

Elena Spinetti

Goethe University FrankfurtORCID 0009-0009-1831-7480Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Gülsün Elif KaragöziD· 2 shared Roberto CovinoiD· 2 shared Adnan MuratoviciD· 1 shared Aleksandra S. AnisimovaiD· 1 shared Benjamin M. R. BourgeoisiD· 1 shared Grzegorz Ścibisz· 1 shared Harald HorneggeriD· 1 shared Isabell NiedermoseriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Gülsün Elif KaragözORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistryeLifePeer-reviewedJul 23, 2026

The Structural Dynamics of IRE1 and its Interaction with Unfolded Peptides

Elena Spinetti, Grzegorz Ścibisz, Gülsün Elif Karagöz, Roberto Covino

This study uses molecular modeling and simulations to clarify how IRE1 detects unfolded proteins, revealing binding pockets and interactions that stabilize oligomers and prevent larger complex formation.

DOI 10.7554/elife.106716

mechanistic / dynamical modelprotein folding & dynamics

𝕏 PostBluesky

BiochemistryNature CommunicationsPeer-reviewedOct 19, 2024

IGF2BP1 phosphorylation regulates ribonucleoprotein condensate formation by impairing low-affinity protein and RNA interactions

Harald Hornegger, Aleksandra S. Anisimova, Adnan Muratovic…·Gülsün Elif Karagöz

This study shows that phosphorylation of IGF2BP1 at S181 and Y396 modulates RNP condensate formation by altering low-affinity interactions with RNA and protein partners.

13 citations

humanproteomics

𝕏 PostBluesky