Author

Stefan Erich Spirig

Institute of Molecular and Clinical Ophthalmology BaselORCID 0009-0009-2243-1710Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Botond RoskaiD· 2 shared Cameron S. CowaniD· 2 shared Magdalena RenneriD· 2 shared Simone PicelliiD· 2 shared Tiago Martins RodriguesiD· 2 shared Yanyan HouiD· 2 shared Adrienn Volak· 1 shared Ákos KusnyerikiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersNeuroscience

Botond RoskaORCID

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2 papers

Recent·Most cited

NeuroscienceNeuronPeer-reviewedMar 30, 2026

Cell type-focused compound screen in human organoids reveals CK1 and MAPK11 inhibition protects cone photoreceptors from death

Stefan Erich Spirig, Álvaro Herrero-Navarro, Larissa Utz…·Botond Roska

The paper screens 2,707 compounds in human retinal organoids to identify those that protect or damage cone photoreceptors, finding CK1 and MAPK11 inhibitors as protective.

12 citationstop 4%

humanexperimental assay

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NeuroscienceCellPeer-reviewedSep 1, 2020

Cell types of the human retina and its organoids at single-cell resolution: developmental convergence, transcriptomic identity, and disease map

Cameron S. Cowan, Magdalena Renner, Martina De Gennaro…·Botond Roska

This study compares cell-type development and transcriptomes in human retinal organoids and adult retinas, finding convergence in transcriptomes and cell-type-specific disease gene expression.

654 citationstop 1%

humanscRNA-seq

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