Christopher W. Dell

The paper develops NucleoNet and DropNet, deep learning models for segmenting nuclei and lipid droplets in EM images, and applies them to compare 2D/3D cancer models with in vivo tumors.

This paper compares two 3D culture models for breast cancer cells, finding that the EmC model better mimics lung metastasis by altering metabolism and gene expression.

The paper uses optogenetic perturbation and electron microscopy to show structural diversity in zebrafish left-right organizer cilia and their role in morphogenesis.

The paper identifies a new external immune organ in zebrafish, the axillary lymphoid organ, suitable for live imaging of immune cell dynamics.