H. J. Yang

This study uses long-read sequencing to precisely map DMD duplications, improving carrier screening and variant classification for Duchenne muscular dystrophy.

The paper uses cryo-EM to study the mechanochemical cycle of full-length human dynein-1, revealing over 40 high-resolution structures and new mechanistic insights.

The paper identifies a novel non-motile dynein heavy chain subfamily, DNAHX, using cryo-EM and shows its evolutionary origin and structural features.

ElixirSeeker uses attention-driven fusion of molecular fingerprints to identify anti-aging compounds, finding four that extend C. elegans lifespan.