Author
Chromosome Engineering Research CenterORCID 0009-0009-4827-2391Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Hiroyuki Satofuka, Satoshi Abe, Takashi Moriwaki…·Yasuhiro Kazuki
The paper compares trans-chromosomic rodent models and finds rats show improved somatic hypermutation and class-switch recombination compared to mice.
Yasuhiro Kazuki, Feng Gao, Miho Yoshida Yamakawa…·Roger H. Reeves
The paper develops a transchromosomic rat model with human chromosome 21 that exhibits key Down syndrome features and provides a tool for DS research and drug development.
Yasuhiro Kazuki, Feng J. Gao, Yicong Li…·Roger H. Reeves
This paper describes a new non-mosaic humanized mouse model of Down syndrome with a nearly complete copy of the long arm of human chromosome 21.