Author

Pengtao Liang

The Francis Crick InstituteORCID 0009-0009-5456-8498Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Bilge ArgunhaniD· 2 shared Lucas KuhleniD· 2 shared Xiaodong ZhangiD· 2 shared Elizabeth A. McCormack· 1 shared Ferdinand KappesiD· 1 shared Janet Zhong· 1 shared Johanna Ertl da CostaiD· 1 shared Kunqi CheniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

Bilge ArgunhanORCID

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintMar 24, 2026

Structures and molecular mechanisms of RAD54B in modulating homologous recombination

Pengtao Liang, Stephanie Tye, Johanna Ertl da Costa…·Xiaodong Zhang

This paper defines the role of RAD54B in homologous recombination using cryo-EM and biochemical assays, showing it stabilizes RAD51 filaments and promotes D-loop formation.

DOI 10.64898/2026.03.22.713441

humanstructural biology

𝕏 PostBluesky

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedDec 3, 2025

RAD51AP1 is a versatile RAD51 modulator

Lucas Kuhlen, Bilge Argunhan, Pengtao Liang…·Xiaodong Zhang

This paper identifies RAD51AP1 as a versatile modulator of RAD51, revealing its role in stabilizing RAD51-ssDNA filaments and promoting strand exchange through multiple binding sites.

3 citations

experimental assaychromatin & epigenetic regulation

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BiochemistrybioRxivPreprintAug 23, 2024

DEK-rRNA interactions regulate ribosome biogenesis and stress response

Nengwei Xu, Kunqi Chen, Malte Prell…·Ferdinand Kappes

This study identifies DEK as a regulator of ribosome biogenesis and stress response through its interaction with rRNA and the 5S RNP-MDM2-p53 axis.

2 citations

humanChIP-seq

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