Xiaodong Zhang

This paper defines the role of RAD54B in homologous recombination using cryo-EM and biochemical assays, showing it stabilizes RAD51 filaments and promotes D-loop formation.

This paper identifies RAD51AP1 as a versatile modulator of RAD51, revealing its role in stabilizing RAD51-ssDNA filaments and promoting strand exchange through multiple binding sites.

This study reveals the mechanism of DNA melting during transcription initiation by σ54-mediated open complex formation, showing how bEBP ATP hydrolysis drives σ54 unfolding and promoter DNA melting.

This study identifies the molecular mechanism by which FIGNL1 disassembles RAD51 filaments from DNA and chromatin, revealing its role in genome stability.