Thea S. Zlatkov

This study shows that aged fibroblasts impair muscle stem cell self-renewal by depositing excessive fibronectin in a 3D hydrogel co-culture system.

This study shows that the aged muscle tissue environment limits muscle stem cell function, and combined interventions can partially restore muscle mass in aged mice.

This study shows that activating FGFR1 restores Integrin-β1-mediated fibronectin sensing in aged satellite cells, improving their regenerative capacity.