Author

Yasemin Sezgin

Nationwide Children's HospitalORCID 0009-0009-7364-5911Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Colin T. MaguireiD· 2 shared Genesis Snyder· 2 shared Meisam Naeimi KararoudiiD· 2 shared Noushin SaljoughianiD· 2 shared Afrooz RashnonejadiD· 1 shared Alexia K. MartiniD· 1 shared Ali A. AshkariD· 1 shared Allison M. BradburyiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Colin T. MaguireORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 30, 2025

Off-the-shelf allogeneic polyclonal CD38KO/CD38-CAR γδT cells for the treatment of T cell malignancies

Genesis Snyder, Alexia K. Martin, Yasemin Sezgin…·Meisam Naeimi Kararoudi

This paper develops CD38KO/CD38-CAR γδT cells for T cell malignancies, showing they effectively target T-ALL without causing fratricide or GvHD.

3 citations

humanproteomics

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GeneticsbioRxivPreprintMay 29, 2025

REMEDY: REpair of heterozygous Mutations independent of Exogenous Donor template with high efficiency using allele specific CRISPR targeting and HDR enhancers

Yasemin Sezgin, Genesis Snyder, Noushin Saljoughian…·Meisam Naeimi Kararoudi

REMEDY enables efficient repair of heterozygous mutations in human and mouse cells without exogenous donor DNA by using CRISPR-induced DSBs and HDR enhancers.

DOI 10.1101/2025.05.29.641201

𝕏 PostBluesky