Cell BiologybioRxivPreprint
Replisome progression regulates R-loop mediated transcriptional repression
Ioannis Tsirkas, Clare S.K. Lee, Daniel Dovrat…·Stephan Hamperl
This study shows that replisome progression through R-loops reverses transcriptional repression and prevents fork stalling by reducing RNAPII density.
DOI 10.1101/2025.07.29.667376