Author

Max Yang Chen

Stanford MedicineORCID 0009-0009-7865-2109Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Assay:imaging· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Birgitt SchüleiD· 4 shared Faria ZafariD· 3 shared C. Alejandra Morato TorresiD· 2 shared Laurin HeinrichiD· 2 shared Aaron HeldiD· 1 shared Ana‐Caroline RauliniD· 1 shared Andrian YangiD· 1 shared Anum KhaniD· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersNeuroscience

Birgitt SchüleORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 17, 2024

Optical Genome Mapping of the human reference iPSC line KOLF2.1J reveals new smaller structural variants in neurodevelopmental genes

Madison James Yang, Kamilla Sedov, Max Yang Chen…·Birgitt Schüle

The paper uses optical genome mapping to identify new smaller structural variants in the KOLF2.1J iPSC line, affecting genes relevant to neurodevelopment.

DOI 10.1101/2024.10.17.618968

humanwhole-genome sequencing

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NeurosciencebioRxivPreprintSep 5, 2023

Robust nuclease-dead S. aureus dCas9-mediated alpha-synuclein knockdown in substantia nigra in a humanized mouse model of Parkinson's disease

C. Alejandra Morato Torres, Faria Zafar, Danuta Sastre…·Birgitt Schüle

This paper demonstrates that sadCas9-mediated CRISPRi reduces alpha-synuclein expression in a humanized mouse model of Parkinson's disease, showing long-term downregulation and attenuated immune response.

5 citations

mouseexperimental assay

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NeuroscienceCell stem cellPeer-reviewedDec 1, 2022

A reference induced pluripotent stem cell line for large-scale collaborative studies

Caroline B. Pantazis, Andrian Yang, Erika Lara…·Florian T. Merkle

The paper identifies and characterizes a reference iPSC line, KOLF2.1J, for standardized use in collaborative studies across multiple differentiation protocols and assays.

323 citationstop 1%

humanwhole-genome sequencing

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NeuroscienceJournal of Neuroscience MethodsPeer-reviewedJun 17, 2022

Multiplex imaging of human induced pluripotent stem cell-derived neurons with CO-Detection by indEXing (CODEX) technology

Laurin Heinrich, Faria Zafar, C. Alejandra Morato Torres…·Birgitt Schüle

This paper applies CODEX multiplex imaging to human iPSC-derived neurons to enable high-resolution biomarker analysis.

6 citations

humanimaging

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