Gabriel Laghlali

This study evaluates adjuvants for a SFTSV vaccine, finding that Addavax and SDI enhance neutralizing antibodies and immune memory, with NP as a key target.

This study evaluates an adjuvanted mucosal vaccine in guinea pigs, showing enhanced protection and reduced viral transmission against influenza.

This study shows that TIV vaccination reduces lethality in influenza-infected mice with secondary pneumococcal infections by modulating immune responses and pathogen titers.

This study identifies CLEC4E as a key driver of pro-inflammatory mDC responses in influenza using single-cell network analysis and validates its therapeutic potential in a murine model.

This study shows that combining TLR7/8 and RIG-I agonists prevents allergic sensitization and reduces influenza severity in OVA-sensitized mice.

This study shows that combining intramuscular mRNA priming with intranasal protein boosting using a combination adjuvant enhances mucosal B- and T-cell responses against SARS-CoV-2 compared to other vaccination regimens.

This study evaluates how lipid nanoparticle (LNP) composition and adjuvant combinations affect immune responses and protection in mice vaccinated against influenza.

This study shows that helpless CD8+ memory T cells, which form without CD4+ help, have transient functional impairments due to prolonged antigen exposure, which resolve over time.