Author

Ranjith Iyappan

Brock UniversityORCID 0009-0009-8526-2192Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Evangelia TsianiiD· 2 shared Mahdi Hejazi Laein· 2 shared Maryam Katoueezadeh· 2 shared Neil E. McCarthyiD· 2 shared Panagiota KlentrouiD· 2 shared Pazhanichamy KalailingamiD· 2 shared Rebecca E. K. MacPhersoniD· 2 shared Ridhi Patel· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

Evangelia TsianiORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 11, 2026

Oxidative Stress-Induced Immunogenic Cell Death Enhances Whole-Cell Vaccine Efficacy in a Syngeneic Pancreatic Cancer Model

Maryam Katoueezadeh, Yazhini Thinakaran, Mahdi Hejazi Laein…·Siu Kwan Sze

This study shows that inducing oxidative stress in pancreatic cancer cells creates an effective whole-cell vaccine that enhances anti-tumor immunity and synergizes with PD-1 blockade.

DOI 10.64898/2026.02.09.704828

mouseproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 8, 2025

IsoDGR-Induced Endothelial Cytoskeletal Disruption Drives Age-Related Blood-Brain Barrier Breakdown

Ridhi Patel, Pazhanichamy Kalailingam, SoFong Cam Ngan…·Siu Kwan Sze

This study identifies isoDGR-induced endothelial cytoskeletal disruption as a key driver of age-related BBB breakdown and shows that targeting isoDGR preserves BBB integrity and reduces neuroinflammation.

DOI 10.1101/2025.07.08.663800

mousebulk RNA-seq

𝕏 PostBluesky