SoFong Cam Ngan

Oxidative Stress-Induced Immunogenic Cell Death Enhances Whole-Cell Vaccine Efficacy in a Syngeneic Pancreatic Cancer Model

This study shows that inducing oxidative stress in pancreatic cancer cells creates an effective whole-cell vaccine that enhances anti-tumor immunity and synergizes with PD-1 blockade.

IsoDGR-Induced Endothelial Cytoskeletal Disruption Drives Age-Related Blood-Brain Barrier Breakdown

This study identifies isoDGR-induced endothelial cytoskeletal disruption as a key driver of age-related BBB breakdown and shows that targeting isoDGR preserves BBB integrity and reduces neuroinflammation.

Anti-isoDGR Antibody Inhibits Atherosclerosis Induced by Western Diet in ApoE-/- mice

This study shows that an anti-isoDGR antibody reduces atherosclerosis and metabolic dysfunction in ApoE-/- mice fed a Western diet.