Author

Grace O Lynch

Broad InstituteORCID 0009-0009-8719-1690Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:deep learning· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Allison Uebele· 1 shared Daytan GibsoniD· 1 shared E L KaplaniD· 1 shared Fengyi ZhengiD· 1 shared Ganna ReintiD· 1 shared John G. DoenchiD· 1 shared Laura M. DrepanosiD· 1 shared Sarra MerzoukiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Allison Uebele

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1 paper

Recent·Most cited

BioengineeringbioRxivPreprintFeb 26, 2026

Optimized parameters for Cas9 CRISPR interference library design

Smriti Srikanth, Fengyi Zheng, Laura M. Drepanos…·John G. Doench

This study designs an optimized Cas9 CRISPRi library by improving on-target scoring and analyzing off-target effects using updated datasets and methods.

2 citations

humanCRISPR screen

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