Daytan Gibson

This study engineers synthetic cargo adaptors to investigate how they modulate dynein activation and transport properties in vitro and in cells.

This study designs an optimized Cas9 CRISPRi library by improving on-target scoring and analyzing off-target effects using updated datasets and methods.

The paper identifies CCSer2 as a protein that gates dynein activity at the cell periphery by inhibiting its regulator Ndel1, enabling spatially restricted dynein activation.