Author

Allison Uebele

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:CRISPR screen· 1 Approach:deep learning· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Daytan GibsoniD· 1 shared E L KaplaniD· 1 shared Fengyi ZhengiD· 1 shared Ganna ReintiD· 1 shared Grace O LynchiD· 1 shared John G. DoenchiD· 1 shared Laura M. DrepanosiD· 1 shared Sarra MerzoukiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioengineering

Daytan GibsonORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Optimized parameters for Cas9 CRISPR interference library design

Smriti Srikanth, Fengyi Zheng, Laura M. Drepanos, Spencer T. Shah, E L Kaplan, Daytan Gibson, Grace O Lynch, Allison Uebele, Ganna Reint, Sarra Merzouk, John G. Doench

This study designs an optimized Cas9 CRISPRi library by improving on-target scoring and analyzing off-target effects using updated datasets and methods.

bioRxiv · Feb 26, 2026 · PreprintBioengineering