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Implications of Spike-glycoprotein processing at S1/S2 by Furin, at S2' by Furin and/or TMPRSS2 and shedding of ACE2: cell-to-cell fusion, cell entry and infectivity of SARS-CoV-2

R. Essalmani, J. Jain, D. Susan-Resiga, U. Andreo, A. Evagelidis, M. Derbali, D. Huynh, F. Dallaire, M. Laporte, A. Delpal, P. Sutto-Ortiz, B. Coutard, C. Mapa, K. Wilcoxen, E. Decroly, T. N. Pham, E. A. Cohen, N. G. Seidah

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Abstract

Disclaimer StatementThe author has withdrawn this manuscript due to a duplicate posting of manuscript number 423106. Therefore, the author does not wish this work to be cited as reference for the project. If you have any questions, please contact the corresponding author (Nabil G. Seidah at seidahn@ircm.qc.ca.

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R. Essalmani, J. Jain, D. Susan-Resiga+15 more·bioRxiv·Dec 18, 2020