Author

T. N. Pham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Spaulding· 2 shared E. A. Cohen· 2 shared H. G. Munshi· 2 shared M. A. Shields· 2 shared A. Delpal· 1 shared A. E. Metropulos· 1 shared A. Evagelidis· 1 shared A. Ismail· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersPathology

C. Spaulding

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Investigating the effects of protons versus x-rays on radiation-induced lymphopenia after brain irradiation

J. Coupey, T. N. Pham, J. Toutain, V. Ivanova, E. HUE, C. Helaine, A. Ismail, R. Saulnier, G. Simonin, M. Rousseau, C. Moignier, J. Thariat, S. Valable

This study compares the effects of proton and x-ray irradiation on lymphopenia and tissue response in mice, finding protons reduce lymphocyte depletion and tissue inflammation.

bioRxiv · Mar 2, 2024 · PreprintCell Biology

BET inhibition rescues ciliogenesis and ameliorates pancreatitis-driven phenotypic changes in mice with Par3 loss.

M. A. Shields, A. E. Metropulos, C. Spaulding, T. Hirose, S. Ohno, T. N. Pham, H. G. Munshi

This study shows that BET inhibition rescues ciliogenesis and reduces pancreatitis-induced damage in mice with Par3 loss.

bioRxiv · Sep 14, 2023 · PreprintPathology

Implications of Spike-glycoprotein processing at S1/S2 by Furin, at S2' by Furin and/or TMPRSS2 and shedding of ACE2: cell-to-cell fusion, cell entry and infectivity of SARS-CoV-2

R. Essalmani, J. Jain, D. Susan-Resiga, U. Andreo, A. Evagelidis, M. Derbali, D. Huynh, F. Dallaire, M. Laporte, A. Delpal, P. Sutto-Ortiz, B. Coutard, C. Mapa, K. Wilcoxen, E. Decroly, , N. G. Seidah

The paper discusses the implications of spike-glycoprotein processing by Furin and TMPRSS2 on SARS-CoV-2 infectivity and cell entry, but the manuscript has been withdrawn.

bioRxiv · Jul 2, 2021 · PreprintBiochemistry

HIV-1 Vpu promotes phagocytosis of infected CD4+ T cells by macrophages through downregulation of CD47

L. Cong, S. M. Sugden, P. Leclair, C. J. Lim, T. N. Pham, E. A. Cohen

This study shows HIV-1 Vpu downregulates CD47 on infected CD4+ T cells, enhancing macrophage phagocytosis and enabling macrophage infection by T/F viruses.

bioRxiv · Mar 16, 2021Microbiology

Gα13 loss promotes tumor progression in the KPC transgenic mouse model of advanced pancreatic cancer

M. A. Shields, C. Spaulding, M. G. Khalafalla, T. N. Pham, H. G. Munshi

The paper shows that Gα13 loss promotes tumor progression in the KPC mouse model of advanced pancreatic cancer but not in the KC model, with increased tumor burden and reduced survival.

bioRxiv · Mar 15, 2021Cancer Biology