Sign in
Synthetic BiologyIFAC-PapersOnLine
Peer-reviewed journal article

A low cost, open source Turbidostat design for in-vivo control experiments in Synthetic Biology

Agostino GuarinoiD, Barbara ShannoniD, Lucia MarucciiD, Claire Suzanne GriersoniD, Nigel J. SaveryiD, Mario di BernardoiD

Abstract

To characterise the dynamics of new engineered systems in Synthetic biology, continuous culture platforms are required. In this paper, after a brief review of the existing machines present in literature, we describe the design and the implementation of a new flexible and low cost turbidostat for in-vivo control experiments. Then, the results of a 3 hours long experiment of control of the Optical Density is reported. Since the foundation of our design is flexibility, in this work we also discuss some possible extensions of our design, with particular attention to their application to validate in-vivo multicellular control design.

PDFDOI

02 /Specification & Classification

Click any tag to browse matching papers
Citations
8
FWCI
0.33
Field percentile
top 46%

Reproducibility ledger

Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.

Sign in to file a reproducibility report.

Similarity Map
SelectedSame fieldCross-field
THISSteel '19Namboothiri '26Cocioba '26Fusco '22May '21Guarino '20
63% semantic matchBioengineering
H. Steel, R. Habgood, C. Kelly+1 more·bioRxiv·Oct 7, 2019