Overlooked features lead to divergent neurobiological interpretations of brain-based machine learning biomarkers
Brendan D. Adkinson, Matthew Rosenblatt, Huili Sun, Javid Dadashkarimi, Link Tejavibulya, Corey L. Horien, Margaret L. Westwater, Raimundo X. Rodriguez, Stephanie Noble, Dustin Scheinost
The paper shows that overlooked brain connectivity features can yield different neurobiological interpretations with similar prediction accuracy in neuroimaging studies.
bioRxiv · Mar 12, 2025 · PreprintNeuroscience