Author

Josie C. Diorio

Douglas Mental Health University Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 4

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Organism:mouse· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Michael Joseph MeaneyiD· 3 shared Tieyuan ZhangiD· 3 shared Nicholas O’TooleiD· 2 shared Patrícia Pelufo SilveiraiD· 2 shared Xianglan Wen· 2 shared Alexander von Friesen· 1 shared Bárbara BarthiD· 1 shared Benjamin C DarwiniD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersNeuroscience

Michael Joseph MeaneyORCID

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4 papers

Recent·Most cited

Resting-state fMRI reveals altered functional connectivity associated with resilience and susceptibility to chronic social defeat stress in mouse brain

Derek Lupinsky, Md Taufiq Nasseef, Carine I. Parent, Kelly Craig, Josie C. Diorio, Tieyuan Zhang, Michael Joseph Meaney

This study uses resting-state fMRI to identify differences in functional connectivity between resilient and susceptible mice after chronic social defeat stress, highlighting brain region interactions linked to stress resilience.

Molecular Psychiatry · Feb 21, 2025Peer-reviewedNeuroscience

Epigenetic signatures of chronic social stress in stress-susceptible animals

Nicholas O’Toole, Tieyuan Zhang, Xianglan Wen, Josie C. Diorio, Patrícia Pelufo Silveira, Benoît Labonté, Eric J. Nestler, Michael Joseph Meaney

The paper identifies epigenetic changes in mice exposed to chronic social defeat stress, showing convergence with human neuroticism pathways.

bioRxiv · Jul 3, 2019 · PreprintNeuroscience

A biologically-informed polygenic score identifiesendophenotypes and clinical conditions associated with the insulinreceptor function on specific brain regions

Shantala A. Hari Dass, Kathryn McCracken, Irina Pokhvisneva, Lawrence M. Chen, Elika Garg, Thao T. T. Nguyen, Zihan Wang, Bárbara Barth, Moein Yaqubi, Lisa M. McEwen, Julie L. MacIsaac, Josie C. Diorio, Michael Steffen Kobor, Kieran J. O’Donnell, Michael Joseph Meaney, Patrícia Pelufo Silveira

The paper introduces a biologically informed polygenic score for insulin receptor-related genes in mesocorticolimbic regions and shows it better predicts childhood impulsivity and early addiction risk than conventional scores.

EBioMedicine · Mar 26, 2019Peer-reviewedNeuroscience

Genetic and behavioural requirements for structural brain plasticity

Dulcie A. Vousden, Alexander von Friesen, Xianglan Wen, Lily R. Qiu, Nicholas O’Toole, Benjamin C Darwin, Leigh Spencer Noakes, Rylan Allemang-Grand, Josie C. Diorio, Paul W. Frankland, Sheena A. Josselyn, Brian J. Nieman, Michael J. Meaney, Tieyuan Zhang, Jason P. Lerch

The paper investigates how environmental enrichment affects brain volume in mice and identifies molecular processes involved, showing CREB is not required for these changes.

bioRxiv · Oct 3, 2018 · PreprintNeuroscience